Our match prediction:
Despite the home advantage Southampton had in the first leg against Midtjylland the Saints didn't manage to start the second leg with a positive goal difference. Midtjylland showed that it's a tough opponent not giving away a lot of chances with a solid defense. In order to reach the semi finals Southampton will need a victory or at least a 2-2 draw. If Midtjylland manages to play as solid as they did during the first leg Midtjylland will qualify for the group stage in the Europa League which can be considered as a surprise.