What is our Hoffenheim vs Lyon prediction?
Our prediction for this match: Hoffenheim 3 - 2 Lyon
Hoffenheim vs Lyon Preview
Hoffenheim will be eager to turn a corner after ending their four-game losing run with a 2-1 Bundesliga victory over Borussia M’gladbach. However, Christian Ilzer’s men still have work to do in Europe after suffering a 3-2 defeat to Besiktas in round two. Bernardo returns from his domestic suspension, while Hajdari and Wimmer are expected to miss out through injury. Hoffenheim’s defensive problems remain a major concern, as they have conceded 2.60 goals per home game, leaving little room for complacency against an in-form opponent.
Lyon, meanwhile, travel to Germany full of confidence after following their 3-2 Europa League triumph over Crystal Palace with a 2-1 Ligue 1 win against Nice. Les Gones have won three consecutive matches across competitions and will fancy their chances of extending that run. However, Openda, Ouedraogo and Tagliafico are unavailable through injury, potentially limiting Paulo Fonseca’s options. Lyon have been particularly solid away from home, conceding just 0.75 goals per game on the road.
Given Hoffenheim’s shaky defence and Lyon’s recent momentum, we are tempted to place our bets on Home Win, alongside Over 2.5 goals and Both Teams to Score.
This Europa League match will be played on Thursday, 22 October 2026 at 20:00.
- League
- Europa League
- Kick-off
- Thu 22 Oct 2026, 20:00UK time
Hoffenheim vs Lyon Betting Tips
| Betting Tip | Odds | Probability |
|---|---|---|
| Match result | ||
| Correct Score: Hoffenheim 3-2 Lyon | 18/1 | |
| Double Chance: 1X | 2/9 | |
| Draw No Bet: TSG Hoffenheim | 3/10 | |
| Half Time/Full Time: TSG Hoffenheim / TSG Hoffenheim | 6/4 | |
| Asian Handicap: TSG Hoffenheim -0.5 | 13/20 | |
| European Handicap: Lyon +2 | 4/9 | |
| Player bets | ||
| Anytime Goalscorer: Andrej Kramaric | 21/20 | |
| First Goalscorer: Andrej Kramaric | 9/2 | |
| To be Booked: Ozan Kabak | 2/1 | |
| Goals | ||
| Both Teams to Score: Yes | 1/2 | |
| Over / Under 1.5 Goals: Over 1.5 Goals | 1/7 | |
| Over / Under 2.5 Goals: Over 2.5 Goals | 4/9 | |
| Over / Under 3.5 Goals: Over 3.5 Goals | 11/10 | |
| Over / Under 4.5 Goals: Over 4.5 Goals | 5/2 | |
| TSG Hoffenheim Clean Sheet: No | 1/3 | |
| Corners | ||
| Total Corners: 9 - 11 | 8/5 | |
Where Can You Place Bets on Hoffenheim vs Lyon?
You can place your bets on Hoffenheim vs Lyon at the following bookmakers:
Min deposit requirement. Free Bets are paid as Bet Credits and are available for use upon settlement of bets to value of qualifying deposit. Min odds, bet and payment method exclusions apply. Returns exclude Bet Credits stake. Time limits and T&Cs apply. Registration required. #Ad / GambleAware.org / 18+
View Offer
18+. GambleAware.org. New GB customers only. Min £10 debit card deposit. Place a £10+ bet at Evens or greater (2.0) each leg on Sports within 7 days. Opt in for £20 in free bets. Valid for 7 days. Geographical restrictions and T&C’s apply. #Ad / GambleAware.org / 18+
View Offer
18+. New customers using Promo code TOP30 only, Min £10/€10/$10 stake, min odds 1.5, free bets paid as 2 x £15/€15/$15, free bets credited after settlement of first qualifying bet, free bets will expire 30 days after the qualifying bet is settled, payment method/player/country restrictions apply. See full terms below. Play responsibly. Gamblingtherapy.org #Ad / GambleAware.org / 18+
View Offer
18+ New UK+ROI customers only. Certain deposit methods & bet types excl. Min first £/€5 bet within 14 days of account reg at min odds 1/2 to get 4 x £/€5 free bets (selected sportsbook markets only, valid 7 days, stake not returned. Restrictions + T&Cs apply. #Ad / GambleAware.org / 18+
View Offer
18+ New UK+ROI Customers only. Certain deposit methods & bet types excl. Min first £/€5 bet within 14 days of account reg at min odds 1/2 to get 4x £/€5 free bets. Free bets available to use on selected sportsbook markets only. Free bets valid for 7 days, stake not returned. Restrictions + T&Cs apply. #Ad / GambleAware.org / 18+
View OfferHoffenheim Team Form and Stats
| Form | Results | Points Per Game |
|---|---|---|
| Overall | wllwlllllw | 0.90 |
| Home | lwlll | 0.60 |
| Away | wlllw | 1.20 |
| Stats | Overall | Home | Away |
|---|---|---|---|
| Win % | 30% | 20% | 40% |
| Average Goals Per Game | 4.10 | 4.60 | 3.60 |
| Scored | 1.90 | 2.00 | 1.80 |
| Conceded | 2.20 | 2.60 | 1.80 |
| BTTS | 80% | 100% | 60% |
| Clean Sheets | 10% | 0% | 20% |
| Failed to Score | 10% | 0% | 20% |
| Expected Goals | 2.10 | 1.89 | 2.27 |
| Expected Goals Against | 1.34 | 1.55 | 1.17 |
Lyon Team Form and Stats
| Form | Results | Points Per Game |
|---|---|---|
| Overall | wldwdwwlww | 2.00 |
| Home | ldwwww | 2.17 |
| Away | wdwl | 1.75 |
| Stats | Overall | Home | Away |
|---|---|---|---|
| Win % | 60% | 67% | 50% |
| Average Goals Per Game | 2.90 | 3.50 | 2.00 |
| Scored | 1.90 | 2.33 | 1.25 |
| Conceded | 1.00 | 1.17 | 0.75 |
| BTTS | 70% | 83% | 50% |
| Clean Sheets | 30% | 17% | 50% |
| Failed to Score | 10% | 0% | 25% |
| Expected Goals | 1.48 | 1.62 | 1.27 |
| Expected Goals Against | 1.44 | 1.40 | 1.49 |
Hoffenheim vs Lyon Head to Head Statistics (H2H)
Hoffenheim (0%)
3 Matches
Lyon (0%)





