MLS Predictions

Chicago Fire

Chicago Fire

Prediction:
3-2

Match Time & Date:

5 October 2025

01:30

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Toronto FC

Toronto FC

Chicago Fire will be aiming to extend their winning run to four games when they take on Toronto FC on Sunday. Chicago Fire look unstoppable in the regular season finale and they must be brimming with confidence ahead of Toronto FC’s visit. Forward Chris Mueller remains on the sidelines with heart problems, but the 29-year-old should be the only absentee in the home team. <... Read More...

This match will be played on 5 October 2025 at 01:30

Austin FC

Austin FC

Prediction:
2-1

Match Time & Date:

5 October 2025

01:30

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St Louis City

St Louis City

Q2 Stadium will host Sunday’s football game between Austin FC and St Louis City. Los Verdes aim to cement their spot in top seven and we predict that they will go all guns blazing at St Louis City. Defender Guilherme Biro serves a one-game ban due to the accumulation of yellow cards, while forward Brandon Vazquez remains in the treatment room. David Critchley’s troops, o... Read More...

This match will be played on 5 October 2025 at 01:30

Philadelphia Union

Philadelphia Union

Prediction:
2-0

Match Time & Date:

5 October 2025

00:30

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New York City

New York City

Buoyed by a thrilling 6-0 win over DC United, Philadelphia Union will be aiming to cement top position in the standings when they take on New York City in the penultimate game of the regular season. Talented forward Quinn Sullivan is rated doubtful for the home side after limping off with injury in the last league game, with Mikael Uhre potentially replacing him in the start... Read More...

This match will be played on 5 October 2025 at 00:30

Orlando City

Orlando City

Prediction:
1-1

Match Time & Date:

5 October 2025

00:30

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Columbus Crew

Columbus Crew

Orlando City will be aiming to seal their spot in the MLS playoffs when they take on Columbus Crew on Sunday morning. The Lions played out a 1-1 draw with Cincinnati at the weekend and, no doubt, they would be happy with one point from the match. Defender Rodrigo Schlegel serves a one-game ban, while all Cartagena, Taifi, and Tsukada are sidelined with injuries.

The ... Read More...

This match will be played on 5 October 2025 at 00:30

New York Red Bulls

New York Red Bulls

Prediction:
2-2

Match Time & Date:

5 October 2025

00:30

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Cincinnati

Cincinnati

New York Red Bulls and FC Cincinnati square off against each other at Red Bull Arena in what is expected to be a close MLS encounter. The Red Bulls experienced all sorts of problems at the back in a 3-2 loss to New York City and, as a result, their playoffs chances have been reduced to a minimum. As New York Red Bulls have nothing to play for in Sunday’s clash, home win sh... Read More...

This match will be played on 5 October 2025 at 00:30

Inter Miami

Inter Miami

Prediction:
2-1

Match Time & Date:

5 October 2025

00:30

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New England Revolution

New England Revolution

Inter Miami will be aiming to recover from a 5-3 loss to Chicago Fire when they take on New England Revolution on Sunday morning. The Herons suffered a shocking loss in midweek, but they are still seen as hot favourites to beat the Revs at their Chase Stadium. David Ruiz remains in the recovery room, while Allen Obando will be assessed ahead of the kick-off. As always, a man... Read More...

This match will be played on 5 October 2025 at 00:30

FC Dallas

FC Dallas

Prediction:
2-1

Match Time & Date:

4 October 2025

21:30

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Los Angeles Galaxy

Los Angeles Galaxy

Toyota Stadium will be the venue when FC Dallas take on Los Angeles Galaxy on Saturday evening. The hosts have been showing steady improvement, winning back-to-back games against Austin FC and Colorado Rapids before battling to a draw with Portland. That run of results has lifted Dallas closer to the playoff spots, and with plenty still to fight for, motivation will not be l... Read More...

This match will be played on 4 October 2025 at 21:30

DC United

DC United

Prediction:
1-2

Match Time & Date:

4 October 2025

19:30

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Charlotte

Charlotte

Audi Field will host Saturday’s clash between DC United and Charlotte. The capital club are desperate to bounce back after suffering a humiliating 6-0 defeat to Philadelphia last time out, a result that further cemented their position at the very bottom of the Eastern Conference. DC United’s problems extend beyond poor form, as Brandon Servania is suspended for this one,... Read More...

This match will be played on 4 October 2025 at 19:30

CF Montreal

CF Montreal

Prediction:
1-2

Match Time & Date:

4 October 2025

19:30

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Nashville

Nashville

Buoyed by a 4-1 win over Charlotte, CF Montreal will look to give fans yet another reason to celebrate when they take on Nashville on Saturday evening. The Canadians quickly bounced back from back-to-back losses to St. Louis City and New York Red Bulls, with the team regaining a much-needed confidence. Montreal, though, missed out on a spot in the playoffs, meaning that they... Read More...

This match will be played on 4 October 2025 at 19:30

Inter Miami

Inter Miami

Prediction:
2-1

Match Time & Date:

1 October 2025

00:30

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Chicago Fire

Chicago Fire

After dropping two points in a 1-1 draw with Toronto FC, Inter Miami will look to return to winning ways in MLS when they take on Chicago Fire on Wednesday morning. The Herons have a chance to overtake New York City in third place in the Eastern Conference and we are positive that they will go all guns blazing at Chicago. Despite failing to find the net in the last league ma... Read More...

This match will be played on 1 October 2025 at 00:30

Cincinnati

Cincinnati

Prediction:
1-1

Match Time & Date:

29 September 2025

00:00

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Orlando City

Orlando City

All eyes will be on TQL Stadium when FC Cincinnati and Orlando City take on each other in a highly-anticipated MLS game. FC Cincinnati aim to retain second place in the standings, but Monday's game will be anything but a walk in the park for the home side. A man to keep an eye on in the home team will be Brenner, who scored a brace in a 3-2 win over Los Angeles Galaxy.

... Read More...

This match will be played on 29 September 2025 at 00:00

Seattle Sounders

Seattle Sounders

Prediction:
2-1

Match Time & Date:

28 September 2025

03:30

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San Jose Earthquakes

San Jose Earthquakes

Seattle Sounders and Vancouver Whitecaps meet at Lumen Field in what is expected to be one of the most exciting games of Sunday's program. Seattle are looking to bounce back from back-to-back defeats to Inter Miami and Austin, and motivation is high with a playoff spot on the line. A victory here would seal their place in the postseason, something their fans expect from such... Read More...

This match will be played on 28 September 2025 at 03:30

When Do We Release MLS Predictions?

With the majority of MLS games being scheduled on the weekends, the MLS predictions and football tips will often be up at the start of the week on either Monday or Tuesday. For midweek games there will be information available during the weekend, in order to give punters a suitable amount of time to analyse the teams.

A lot of people tend to believe that you can telegraph what’s going to happen in Major League Soccer more so than you can elsewhere, but we honestly believe that couldn’t be any further from the truth.

This is an exciting league full of many twists and turns, and because it’s so young, the possibilities are endless for what the next few years could hold.

MLS Predictions by FootballPredictions.com

Major League Soccer is the premier football league in the United States of America, and it’s been that way ever since the first season came to fruition in 1996. As a part of the CONCACAF, the MLS plays host to three Canadian teams with the rest stemming from the United States, currently being 24 operational teams on a week to week basis.

Summers are for MLS

The regular season runs from March all the way through until October, with the team with the best record being given the Supporters’ Shield. From that point on 14 teams compete in the MLS Cup Playoffs, before eventually being dwindled down to two: who then compete in the MLS Cup.

The MLS keeps on rising

The league struggled in its first few seasons but has really come firing out of the blocks in the last decade or so, with the signings of star players from around the world certainly helping. They get higher average crowds than the NBA and NHL, with the most successful team being LA Galaxy from Los Angeles (5 MLS Cups and 4 Supporters Shields).

MLS Tips, Predictions and Betting advice

It’ll go without saying to a lot of folks out there, but you should probably look for the superstars. Whilst the likes of Wayne Rooney, Carlos Vela and Zlatan Ibrahimovic aren’t going to single-handedly lead their team to victory every week, they’re certainly going to play influential roles. With that in mind, you should take a real hard look at the starting XIs – because defensively speaking, there’s a lot of vulnerability on display in the MLS.

Tough and rough playing style

In addition to that, you should prepare for quite a few yellow and red cards throughout the course of most game weeks. These guys go in pretty hard on a regular basis, and with that kind of intensity, MLS tips that are based on standard play could go flying out of the window.

Mainly, though, when it comes to your MLS football predictions, keep an eye on momentum, because the American sports franchises thrive off of big runs late in the season. The allure of the playoffs always leads to teams upping their game, so if you’re betting late in the campaign, make sure to keep that in mind.

Our Team Of MLS Experts

Despite Major League Soccer still being in its infancy when compared to some of the other major leagues situated around world football, we’ve still been able to build up a solid collection of experts that provide top MLS tips from the first week of the season right up until the very last.

They’re located around the United States and beyond, with one of their primary tools being their ability to compare and contrast the American style with the European style. In addition to that, they also monitor the ‘lower leagues’ of American football pretty closely, which is especially important when you see some of these expansion franchises being brought into the mix.

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