MLS Predictions

San Diego FC

San Diego FC

Prediction:
2-0

Match Time & Date:

28 September 2025

03:30

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San Jose Earthquakes

San Jose Earthquakes

San Diego FC welcome San Jose Earthquakes to Snapdragon Stadium in the closing stages of the regular season. The hosts want to retain top position in the Western Conference, aiming to crown an impressive campaign with another three points. Even though Alvarado, Ingvartsen, Negri, and Verhoeven are all sidelined, the depth in the squad has carried them through difficult momen... Read More...

This match will be played on 28 September 2025 at 03:30

Portland Timbers

Portland Timbers

Prediction:
1-1

Match Time & Date:

28 September 2025

03:30

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FC Dallas

FC Dallas

Portland Timbers take on FC Dallas at Providence Park in a clash that could prove vital in the playoff race. Both sides are eyeing a top-nine finish, but Dallas arrive in slightly better form after back-to-back wins over Austin and Colorado. The visitors have found confidence in attack, yet injury problems could slow them down with Geovane Jesus, Newman, Paes, and Pomykal al... Read More...

This match will be played on 28 September 2025 at 03:30

Los Angeles Galaxy

Los Angeles Galaxy

Prediction:
2-1

Match Time & Date:

28 September 2025

03:30

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Sporting Kansas City

Sporting Kansas City

Los Angeles Galaxy and Sporting Kansas City, the two teams that missed out on a spot in the playoffs, face each other at Dignity Health Sports Park on Sunday morning. LA Galaxy have been involved in some high-scoring games of late and we predict that they will stick to their attacking style of play against Sporting. Midfielder Isaiah Parente is banned for the hosts, while al... Read More...

This match will be played on 28 September 2025 at 03:30

Real Salt Lake

Real Salt Lake

Prediction:
1-0

Match Time & Date:

28 September 2025

02:30

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Austin FC

Austin FC

Real Salt Lake play host to Austin FC at their America First Field in what is expected to be an entertaining contest. The Royals aim to recover from a 4-1 loss to Los Angeles FC and a win over Austin FC will see them stay in the playoffs race. You should bear in mind, though, that Real Salt Lake have suffered four defeats in the previous five league matches. The good news fo... Read More...

This match will be played on 28 September 2025 at 02:30

Colorado Rapids

Colorado Rapids

Prediction:
1-0

Match Time & Date:

28 September 2025

02:30

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Minnesota United

Minnesota United

Colorado Rapids will be aiming to retain their spot in top nine when they take on Minnesota United in what promises to be an exciting MLS game. The Rapids have been having their ups and downs of late, but a win over Minnesota will see them move one step closer to booking their spot in the playoffs. Midfielder Kimani Stewart-Baynes should be the only absentee in the home team... Read More...

This match will be played on 28 September 2025 at 02:30

St Louis City

St Louis City

Prediction:
2-3

Match Time & Date:

28 September 2025

01:30

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Los Angeles FC

Los Angeles FC

St Louis City will be aiming to claim a major scalp when they take on Los Angeles FC in a highly-anticipated MLS game. St Louis City proved their worth in back-to-back wins over CF Montreal (2-0) and San Jose Earthquakes, but that will not help them book their spot in the playoffs. Brendan McSorley should keep his place in the starting XI after scoring a brace against San Jo... Read More...

This match will be played on 28 September 2025 at 01:30

Nashville

Nashville

Prediction:
2-1

Match Time & Date:

28 September 2025

01:30

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Houston Dynamo

Houston Dynamo

Nashville will try to put an end to their three-game losing run in the Major League Soccer when they take on Houston Dynamo on Sunday morning. The Boys in Gold suffered a dip in form, but a win over Houston Dynamo will see them stay in the playoffs berth. All Gaines, Meyer, Perez, and Washington are out of contention with injuries, but there are no suspended players in the h... Read More...

This match will be played on 28 September 2025 at 01:30

Chicago Fire

Chicago Fire

Prediction:
1-1

Match Time & Date:

28 September 2025

01:30

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Columbus Crew

Columbus Crew

Buoyed by a 3-0 win over Minnesota United, Chicago Fire will look to give fans yet another reason to celebrate when they take on Columbus Crew on Sunday morning. Chicago Fire quickly bounced back from a 3-1 loss to New York City, with the team regaining a much-needed confidence, but they have yet to secure their spot in the playoffs. Bearing any fresh injury worries, Gregg B... Read More...

This match will be played on 28 September 2025 at 01:30

New York Red Bulls

New York Red Bulls

Prediction:
2-1

Match Time & Date:

28 September 2025

00:30

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New York City

New York City

There will be fireworks when New York Red Bulls and New York City lock horns in a highly-anticipated local derby. New York Red Bulls aim to build on a 2-0 win over CF Montreal and a triumph over New York City could see them climb to the playoffs berth. All Bogacz, Harper, Marucci, and Morgan miss out with injuries for the home team.

The Blue Pigeons, on the other han... Read More...

This match will be played on 28 September 2025 at 00:30

New England Revolution

New England Revolution

Prediction:
2-2

Match Time & Date:

28 September 2025

00:30

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Atlanta United

Atlanta United

New England and Atlanta United take on each other at Gillette Stadium in what is expected to be an interesting contest. The Revs have already missed out on the playoffs, and their current form underlines their struggles. A four-game winless streak has drained confidence, and with Peyton Miller suspended, depth issues add further concerns. Still, with no pressure left, the ho... Read More...

This match will be played on 28 September 2025 at 00:30

DC United

DC United

Prediction:
1-2

Match Time & Date:

28 September 2025

00:30

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Philadelphia Union

Philadelphia Union

Audi Field will host the Eastern Conference encounter between DC United and Philadelphia Union. DC United failed to secure a playoff berth, but they will still be keen to end their campaign in style. The capital club will be without Badji and Fletcher through injuries, while Randall Leal faces a race against time to prove his fitness. Pride is all that is left to play for, y... Read More...

This match will be played on 28 September 2025 at 00:30

Charlotte

Charlotte

Prediction:
2-0

Match Time & Date:

28 September 2025

00:30

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CF Montreal

CF Montreal

Bank of America Stadium will host a clash between Charlotte and Montreal. Following five straight victories, Charlotte fell to a 2-0 defeat at New York City, but The Crown remain firmly in the playoff picture and are eager to bounce back in front of their own fans. Their home form has been particularly impressive, and with Harry Toffolo the only absentee, they will fancy the... Read More...

This match will be played on 28 September 2025 at 00:30

When Do We Release MLS Predictions?

With the majority of MLS games being scheduled on the weekends, the MLS predictions and football tips will often be up at the start of the week on either Monday or Tuesday. For midweek games there will be information available during the weekend, in order to give punters a suitable amount of time to analyse the teams.

A lot of people tend to believe that you can telegraph what’s going to happen in Major League Soccer more so than you can elsewhere, but we honestly believe that couldn’t be any further from the truth.

This is an exciting league full of many twists and turns, and because it’s so young, the possibilities are endless for what the next few years could hold.

MLS Predictions by FootballPredictions.com

Major League Soccer is the premier football league in the United States of America, and it’s been that way ever since the first season came to fruition in 1996. As a part of the CONCACAF, the MLS plays host to three Canadian teams with the rest stemming from the United States, currently being 24 operational teams on a week to week basis.

Summers are for MLS

The regular season runs from March all the way through until October, with the team with the best record being given the Supporters’ Shield. From that point on 14 teams compete in the MLS Cup Playoffs, before eventually being dwindled down to two: who then compete in the MLS Cup.

The MLS keeps on rising

The league struggled in its first few seasons but has really come firing out of the blocks in the last decade or so, with the signings of star players from around the world certainly helping. They get higher average crowds than the NBA and NHL, with the most successful team being LA Galaxy from Los Angeles (5 MLS Cups and 4 Supporters Shields).

MLS Tips, Predictions and Betting advice

It’ll go without saying to a lot of folks out there, but you should probably look for the superstars. Whilst the likes of Wayne Rooney, Carlos Vela and Zlatan Ibrahimovic aren’t going to single-handedly lead their team to victory every week, they’re certainly going to play influential roles. With that in mind, you should take a real hard look at the starting XIs – because defensively speaking, there’s a lot of vulnerability on display in the MLS.

Tough and rough playing style

In addition to that, you should prepare for quite a few yellow and red cards throughout the course of most game weeks. These guys go in pretty hard on a regular basis, and with that kind of intensity, MLS tips that are based on standard play could go flying out of the window.

Mainly, though, when it comes to your MLS football predictions, keep an eye on momentum, because the American sports franchises thrive off of big runs late in the season. The allure of the playoffs always leads to teams upping their game, so if you’re betting late in the campaign, make sure to keep that in mind.

Our Team Of MLS Experts

Despite Major League Soccer still being in its infancy when compared to some of the other major leagues situated around world football, we’ve still been able to build up a solid collection of experts that provide top MLS tips from the first week of the season right up until the very last.

They’re located around the United States and beyond, with one of their primary tools being their ability to compare and contrast the American style with the European style. In addition to that, they also monitor the ‘lower leagues’ of American football pretty closely, which is especially important when you see some of these expansion franchises being brought into the mix.

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