MLS Predictions

Los Angeles Galaxy

Los Angeles Galaxy

Prediction:
1-2

Match Time & Date:

21 September 2025

03:30

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Cincinnati

Cincinnati

Los Angeles Galaxy play host to FC Cincinnati at Dignity Health Sports Park as the Eastern Conference races heat up. The Galaxy have nothing left to play for in terms of playoff qualification, having already missed out on a top-nine finish, but pride will be at stake in front of their supporters. Despite a disappointing campaign, LA remain a team capable of producing flashes... Read More...

This match will be played on 21 September 2025 at 03:30

Sporting Kansas City

Sporting Kansas City

Prediction:
2-3

Match Time & Date:

21 September 2025

01:30

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Vancouver Whitecaps

Vancouver Whitecaps

Sporting Kansas City and Vancouver Whitecaps take on each other in what could be a playoff-defining match. Kansas City aim to keep their playoff hopes alive, but they enter this with a shaky run, having suffered four defeats in their previous five league matches. Vancouver want to build on a thrilling 7-0 win over Philadelphia Union, riding high and confident. Sporting are m... Read More...

This match will be played on 21 September 2025 at 01:30

Minnesota United

Minnesota United

Prediction:
1-1

Match Time & Date:

21 September 2025

01:30

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Chicago Fire

Chicago Fire

Minnesota United take on Chicago Fire at Allianz Field in a crucial MLS showdown. Minnesota have already booked their place in the playoffs, but they surely want to overtake San Diego FC for top spot in the Western Conference. The hosts, however, will be without Hassani Dotson (meniscus injury) and Ho-Yeon Jung (season-ending torn ACL).

Chicago Fire, on the other sid... Read More...

This match will be played on 21 September 2025 at 01:30

Houston Dynamo

Houston Dynamo

Prediction:
1-1

Match Time & Date:

21 September 2025

01:30

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Portland Timbers

Portland Timbers

Houston Dynamo and Portland Timbers take on each other at Shell Energy Stadium in the race for playoff positions. The Dynamo are desperate to climb into the top nine, producing far better displays in front of home fans compared to their away performances. They showed character in recent matches, and even though Artur is unavailable due to suspension, the Orange Crush still l... Read More...

This match will be played on 21 September 2025 at 01:30

FC Dallas

FC Dallas

Prediction:
1-0

Match Time & Date:

21 September 2025

01:30

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Colorado Rapids

Colorado Rapids

FC Dallas play host to Colorado Rapids in a six-pointer at Toyota Stadium. The Toros boosted their playoff hopes with a confidence-building 2-0 win over state rivals Austin FC, and they will be aiming to keep momentum going in front of their supporters. The return of goalkeeper Michael Collodi from suspension provides extra stability at the back, while Dallas’ attacking un... Read More...

This match will be played on 21 September 2025 at 01:30

Orlando City

Orlando City

Prediction:
2-1

Match Time & Date:

21 September 2025

00:30

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Nashville

Nashville

Orlando City play host to Nashville SC in what promises to be an exciting MLS clash. The Lions are eager to cement their spot in the playoffs berth as they eye their third consecutive win at home. Their attacking line looks stronger than ever with key forward Luis Muriel back from suspension, and confidence is high following recent victories. Orlando’s defense has also tig... Read More...

This match will be played on 21 September 2025 at 00:30

Inter Miami

Inter Miami

Prediction:
4-1

Match Time & Date:

21 September 2025

00:30

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DC United

DC United

Buoyed by a 3-1 win over Seattle Sounders, Inter Miami will look to give fans yet another reason to celebrate when they face DC United at their Chase Stadium on Sunday morning. The Herons are sitting in sixth place in the Eastern Conference, but you should bear in mind that they have three games in hand. As always, a man to watch in the home team will be Leo Messi, who score... Read More...

This match will be played on 21 September 2025 at 00:30

Columbus Crew

Columbus Crew

Prediction:
2-0

Match Time & Date:

21 September 2025

00:30

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Toronto FC

Toronto FC

Following a 3-2 loss at New York City, Columbus Crew will look to get back on course in the Major League Soccer when they face Toronto FC on Sunday. Columbus are determined to retain their spot in top seven and we predict that they will adopt an attack-oriented approach against Toronto FC. There are no fresh injury worries in the home team, but all Rossi, Camacho, and Zawads... Read More...

This match will be played on 21 September 2025 at 00:30

CF Montreal

CF Montreal

Prediction:
1-2

Match Time & Date:

21 September 2025

00:30

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New York Red Bulls

New York Red Bulls

CF Montreal will try to recover from a 2-0 loss to St. Louis City when they take on New York Reds Bulls on Sunday morning. The Canadians are stuck at the bottom of the table with only 24 points on their account and, as a result, they will not take part in the MLS playoffs. Given their poor display in the defeat to St. Louis City, we do not believe that there is a big value i... Read More...

This match will be played on 21 September 2025 at 00:30

Atlanta United

Atlanta United

Prediction:
0-2

Match Time & Date:

20 September 2025

21:30

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San Diego FC

San Diego FC

San Diego FC will be aiming to retain top position in the Western Conference when they take on Atlanta United in the closing match of Saturday’s program. The newcomers are enjoying a successful debut season and they surely want to put icing on the cake. Fit-again forward Corey Baird is pushing for a rare start, while both Alvarado and Reyes are sidelined with injuries. ... Read More...

This match will be played on 20 September 2025 at 21:30

Philadelphia Union

Philadelphia Union

Prediction:
3-0

Match Time & Date:

20 September 2025

19:30

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New England Revolution

New England Revolution

Philadelphia Union will be aiming to recover from a heavy 7-0 loss to Vancouver Whitecaps when they take on New England on Saturday evening. The U’s are eager to clinch top position in the Eastern Conference, but the lack of confidence could prove to be a big problem for the home side this time out. It has to be noted that both Jovan Lukic and Olwethu Makhanya are banned f... Read More...

This match will be played on 20 September 2025 at 19:30

New York City

New York City

Prediction:
2-1

Match Time & Date:

20 September 2025

17:00

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Charlotte

Charlotte

New York City will be aiming to build on back-to-back wins over Chicago Fire and Columbus Crew when they face Charlotte on Saturday evening. The Blue Pigeons have been scoring goals for fun of late and they are likely to stick to their attacking style of play against Charlotte. A man to keep an eye on in the home team will be Hannes Wolf, who scored a brace in the last leagu... Read More...

This match will be played on 20 September 2025 at 17:00

Author image
Bojan Jovanovic • Football expert
25 January 2026 • 15:36 UTC • 1 min read
MLS Predictions

Weekly MLS Betting Tips

Below you’ll find our expert tips for the Major League Soccer (MLS), covering the most popular football betting markets such as Match Result, Both Teams to Score (BTTS), Over/Under 2.5 Goals, Total Goals, and Correct Score. Our MLS betting tips are updated weekly to reflect team form, tactical setups, and player availability across both the Eastern and Western Conferences.

MLS Betting Tips

MatchBetting tips
Columbus CrewColumbus CrewPhiladelphia UnionPhiladelphia Union26/04/2026, 00:30
  • Correct Score: 2-2
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Draw
DC UnitedDC UnitedOrlando CityOrlando City26/04/2026, 00:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
CincinnatiCincinnatiNew York Red BullsNew York Red Bulls26/04/2026, 00:30
  • Correct Score: 3-3
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 14.5
  • Match Result: Draw
Inter MiamiInter MiamiNew England RevolutionNew England Revolution26/04/2026, 00:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Austin FCAustin FCHouston DynamoHouston Dynamo26/04/2026, 01:30
  • Correct Score: 2-2
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Draw
Chicago FireChicago FireSporting Kansas CitySporting Kansas City26/04/2026, 01:30
  • Correct Score: 2-0
  • BTTS: No
  • Over 1.5 Goals: Yes
  • Total SoT: Over 4.5
  • Match Result: Home Win
Nashville SCNashville SCCharlotteCharlotte26/04/2026, 01:30
  • Correct Score: 1-0
  • BTTS: No
  • Over 1.5 Goals: No
  • Total SoT: Over 2.5
  • Match Result: Home Win
St Louis CitySt Louis CitySan Jose EarthquakesSan Jose Earthquakes26/04/2026, 01:30
  • Correct Score: 1-3
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Away Win
San Diego FCSan Diego FCPortland TimbersPortland Timbers26/04/2026, 02:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Seattle SoundersSeattle SoundersFC DallasFC Dallas26/04/2026, 02:30
  • Correct Score: 3-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Home Win
Vancouver WhitecapsVancouver WhitecapsColorado RapidsColorado Rapids26/04/2026, 02:30
  • Correct Score: 2-0
  • BTTS: No
  • Over 1.5 Goals: Yes
  • Total SoT: Over 4.5
  • Match Result: Home Win
Los Angeles GalaxyLos Angeles GalaxyReal Salt LakeReal Salt Lake27/04/2026, 00:00
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Toronto FCToronto FCSan Jose EarthquakesSan Jose Earthquakes02/05/2026, 18:00
  • Correct Score: 1-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 4.5
  • Match Result: Draw
Sporting Kansas CitySporting Kansas CitySeattle SoundersSeattle Sounders02/05/2026, 19:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Real Salt LakeReal Salt LakePortland TimbersPortland Timbers02/05/2026, 21:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Inter MiamiInter MiamiOrlando CityOrlando City03/05/2026, 00:00
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Atlanta UnitedAtlanta UnitedCF MontrealCF Montreal03/05/2026, 00:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Columbus CrewColumbus CrewMinnesota UnitedMinnesota United03/05/2026, 00:30
  • Correct Score: 2-2
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Draw
New England RevolutionNew England RevolutionCharlotteCharlotte03/05/2026, 00:30
  • Correct Score: 1-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 4.5
  • Match Result: Draw
New York Red BullsNew York Red BullsFC DallasFC Dallas03/05/2026, 00:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Philadelphia UnionPhiladelphia UnionNashville SCNashville SC03/05/2026, 00:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Chicago FireChicago FireCincinnatiCincinnati03/05/2026, 01:30
  • Correct Score: 2-2
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Draw
Houston DynamoHouston DynamoColorado RapidsColorado Rapids03/05/2026, 01:30
  • Correct Score: 1-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 4.5
  • Match Result: Draw
San Diego FCSan Diego FCLos Angeles FCLos Angeles FC03/05/2026, 02:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
Los Angeles GalaxyLos Angeles GalaxyVancouver WhitecapsVancouver Whitecaps03/05/2026, 03:30
  • Correct Score: 2-1
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 7.5
  • Match Result: Home Win
New York CityNew York CityDC UnitedDC United03/05/2026, 20:00
  • Correct Score: 2-2
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Draw
Austin FCAustin FCSt Louis CitySt Louis City03/05/2026, 22:30
  • Correct Score: 2-2
  • BTTS: Yes
  • Over 1.5 Goals: Yes
  • Total SoT: Over 9.5
  • Match Result: Draw

MLS Betting Stats and Data

Our MLS betting analysis is based on comprehensive data from North America’s top professional football league. We evaluate essential betting statistics such as goal averages, BTTS rates, and clean sheet frequencies to assess team balance and playing style. These figures are used to generate data-driven football betting tips, highlighting where trends in scoring, home advantage, and defensive reliability align with strong market value. Recent MLS seasons have produced an average of around 2.9 goals per match, with home teams winning roughly 47% of the time. The league’s mix of fast-paced attacking football and travel-related fatigue patterns makes MLS betting tips particularly valuable for goal-oriented markets such as Over 2.5 Goals and Both Teams to Score (BTTS).

MLS Stats (2025)

Team Type Average Goals Scored
Home Teams 1.66
Away Teams 1.36
Total (Combined) 3.02
29.8 min/Goal (1629 Goals in 540 matches)
47% Clean Sheets (253 times out of 540 matches)
60% Both Teams Scored (322 times out of 540 matches)
Outcome (Full-Time Result) % of Matches
Home Win 44%
Draw 25%
Away Win 31%
Goals % of Matches Over
Over 0.5 94%
Over 1.5 78%
Over 2.5 59%
Over 3.5 36%
Over 4.5 20%
Goals % of Matches Under
Under 0.5 6%
Under 1.5 22%
Under 2.5 41%
Under 3.5 64%
Under 4.5 80%
MLS Match Stats (2025)
Shots Per Match 25.5
Shots / Match (Home) 14.01
Shots / Match (Away) 11.49
Fouls Per Match 24.19
Fouls / Match (Home) 12.03
Fouls / Match (Away) 12.16
Offsides Per Match 3.53
Players Participated 970

Related Leagues We Cover

Explore more of the world’s leading football tournaments with our expert predictions and betting tips connected to Major League Soccer.

  • Premier League Predictions. Our Premier League predictions analyse England’s top flight, focusing on tactical balance, player form, and key betting markets.
  • Champions League Predictions. Champions League forecasts study Europe’s elite competition, highlighting high-pressure knockout rounds and tactical contrasts.
  • Europa League Predictions. Our Europa League predictions assess Europe’s secondary competition, identifying value in unpredictable fixtures and squad rotations.
  • Gold Cup Predictions. Gold Cup forecasts cover North America’s premier international event, linking MLS form with performances from the USA, Canada, and Mexico.
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