St Mary’s Stadium will be the centre of attention when Southampton take on Arsenal in the FA Cup quarter-finals. As Arsenal are a more experienced side, our prediction leans toward a 2-1 away win. Tonda Eckert's troops continue their impressive cup run after shocking Fulham in the last 16 and arrive in fine form, winning 8 of their last 10 matches across all competitions. The Saints have averaged 2.2 goals scored and just 0.8 conceded per game recently, keeping 40% clean sheets and scoring in every match over this run.
Arsenal, aiming to bounce back from their EFL Cup final loss to Manchester City, will be without Eberechi Eze, Martin Odegaard, and Mikel Merino. Despite these absences, the Gunners remain strong, averaging 2.0 goals scored and 0.8 conceded over their last 10 games, with a 40% clean sheet rate and BTTS in 50% of matches. Historically, the fixture has favored Arsenal, who have won 46% of the 28 encounters.
Taking everything into account, we predict an entertaining clash with goals likely from the home side, while Arsenal look to advance to the FA Cup semis. Therefore, Away Win is our main betting tip, alongside BTTS (54% H2H) and Over 2.5 goals (50%).
This FA Cup match will be played on Saturday 4 April 2026 at 20:00.
What is our Southampton vs Arsenal prediction?
Our prediction for this match: Southampton 1 - 2 Arsenal
Southampton vs Arsenal Betting Tips
- Correct Score: 1-2 @ 750 Odds
- Both Teams to Score (BTTS): Yes @ -125 Odds
- Over / Under 4.5 Goals: Under 4.5 Goals @ -450 Odds
- Over / Under 3.5 Goals: Under 3.5 Goals @ -175 Odds
- Over / Under 2.5 Goals: Over 2.5 Goals @ -188 Odds
- Over / Under 1.5 Goals: Over 1.5 Goals @ -600 Odds
- Anytime Goalscorer: Gabriel Jesus @ 100 Odds
- First Goalscorer: Gabriel Jesus @ 400 Odds
- To be Booked: Ryan Manning @ 240 Odds
- Asian Handicap: Southampton +1.5 @ -134 Odds
- European Handicap: Arsenal +1 @ -550 Odds
- Shots on Target (Home): Over 2.5
- Shots on Target (Away): Over 4.5
- Shots on Target (Total): Over 7.5
- Total Corners: 9 - 11 @ 162 Odds
- Double Chance: 12 @ -600 Odds
- Draw No Bet: Arsenal to Win @ -700 Odds
- Half Time/Full Time: Arsenal to Win/Arsenal to Win @ 100 Odds
- Clean Sheet: Arsenal - No @ -163 Odds
Where Can You Place Bets on Southampton vs Arsenal?
You can place your bets on Southampton vs Arsenal at the following bookmakers:
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View OfferSouthampton Team Form and Stats
| Form | Results | Points Per Game |
|---|---|---|
| Overall | wwdwwwdwww | 2.60 |
| Home | wdwww | 2.60 |
| Away | wwwdw | 2.60 |
| Stats | Overall | Home | Away |
|---|---|---|---|
| Win % | 80% | 80% | 80% |
| Average Goals Per Game | 3.00 | 2.60 | 3.40 |
| Scored | 2.20 | 2.20 | 2.20 |
| Conceded | 0.80 | 0.40 | 1.20 |
| BTTS | 60% | 40% | 80% |
| Clean Sheets | 40% | 60% | 20% |
| Failed to Score | 0% | 0% | 0% |
| Expected Goals | 1.60 | 1.84 | 1.35 |
| Expected Goals Against | 1.41 | 1.18 | 1.63 |
Arsenal Team Form and Stats
| Form | Results | Points Per Game |
|---|---|---|
| Overall | wdwwwwdwwl | 2.30 |
| Home | wwwwl | 2.40 |
| Away | dwwwd | 2.20 |
| Stats | Overall | Home | Away |
|---|---|---|---|
| Win % | 70% | 80% | 60% |
| Average Goals Per Game | 2.80 | 2.60 | 3.00 |
| Scored | 2.00 | 2.00 | 2.00 |
| Conceded | 0.80 | 0.60 | 1.00 |
| BTTS | 50% | 20% | 80% |
| Clean Sheets | 40% | 60% | 20% |
| Failed to Score | 10% | 20% | 0% |
| Expected Goals | 1.75 | 1.98 | 1.52 |
| Expected Goals Against | 1.08 | 0.99 | 1.16 |
Southampton vs Arsenal Head to Head Statistics (H2H)
Southampton (25%)
28 Matches
Arsenal (46%)
Inter
Cagliari
Brentford
Fulham
Newcastle
Bournemouth
Leeds United
Wolves
Napoli
Lazio
Frankfurt
Leipzig
